R-1,3-Butanediol: Production and Safety
We utilize R-1,3 Butanediol (“R-1,3-BDO”) in Ketone-IQ for many reasons: safety, sustainability, and efficacy included.
Safe
The history of R-1,3-BDO supplementation research goes back a long time and its effects and safety are well understood. Other Ketone supplements, like the “Ketone Ester” (D-BHB, R-1,3-BDO Monoester) were developed recently, in the last 15-20 years, however R-1,3-BDO has been studied since the 60's-70's!
A few notable studies:
- Long Term: Participants ingested 15g/day for 14 days and no significant adverse effects were observed. [Kies C, Tobin RB, Fox HM, Mehlman MA (1973). Utilization of 1,3-butanediol and nonspecific nitrogen in human adults*. J Nutr 103(8):1155-1163. DOl :10.1093/ jn/ 103.8.1155]*
- Large doses — Participants ingested 40g/day for 5 days and no significant adverse effects were observed. [Tobin RB, Mehlman MA, Kies C, Fox HM, Soeldner JS (1975). Nutritional and metabolic studies in humans with 1,3-butanediol. Fed Proc 34(12):2171-2176]
As a final and official certification of safety, R-1,3,-BDO has GRAS (”Generally Regarded as Safe”) status, based on a comprehensive review of decades of scientific literature and clinical data.
Ketone-IQ is 3rd-party-certified through NSF and NSF Certified for Sport, listed in the NSF catalog for sports nutrition.
Natural and Sustainable
- Natural and Bio-Identical: R-1,3-BDO occurs naturally in foods like avocados, coconuts, honey, and mint.
- Sustainably Fermented: Our R-,1,3-BDO is made through a specialized and sustainable fermentation process, using non-GMO sugar as a starting material. Think: high-tech, non-GMO kombucha!
Effective
We have a lot to say on this topic!
For a fulsome writeup on why we believe Ketone-IQ to be the most optimal Ketone supplement on the planet, read more here: https://help.ketone.com/article/f1qg9hefji-how-does-ketone-iq-compare-to-other-ketone-supplements
